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Fig. 3 | Cell Communication and Signaling

Fig. 3

From: JAK1 inactivation promotes proliferation and migration of endometrial cancer cells via upregulating the hypoxia-inducible factor signaling pathway

Fig. 3

Functional enrichment analyses of the differentially expressed genes by JAK depletion. A Volcano plot of the differentially expressed genes in parental and JAK1-knockdown KLE cells. Red dots represent up-regulated genes and blue dots represent down-regulated genes. B Heatmap depicting the expression of the top 50 differentially expressed genes in parental and JAK1-knockdown KLE cells. The left vertical axis shows clusters of differentially expressed genes and the right vertical axis represents gene names. Red represents upregulated genes and blue represents downregulated genes. C Go analysis of the differentially expressed genes in parental and JAK1-knockdown KLE cells (biological process). D KEGG pathway analysis of the differentially expressed genes in parental and JAK1-knockdown KLE cells

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Cell Communication and Signaling

ISSN: 1478-811X