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Fig. 2 | Cell Communication and Signaling

Fig. 2

From: JAK1 inactivation promotes proliferation and migration of endometrial cancer cells via upregulating the hypoxia-inducible factor signaling pathway

Fig. 2

JAK1 suppresses EC cell growth and migration. A Western blotting of the indicated proteins in WCLs (whole cell lysates) from six endometrial cancer lines. B Western blotting of the indicated proteins in WCLs from KLE and SPEC-2 cells expressing sh ctrl, JAK1-sh1, or JAK1-sh2. C, D CCK-8 cell proliferation analysis of KLE and SPEC-2 cells expressing sh ctrl, JAK1-sh1, or JAK1-sh2. Data are shown as the mean ± SD (n = 3). E, F Colony formation analysis of KLE and SPEC-2 cells expressing sh ctrl, JAK1-sh1, or JAK1-sh2. Data are shown as the mean ± SD (n = 3). Scale bar, 100 μm. G, H Transwell migration analysis of KLE and SPEC-2 cells expressing sh ctrl, JAK1-sh1, or JAK1-sh2. Data are shown as the mean ± SD (n = 3). Scale bar, 100 μm

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Cell Communication and Signaling

ISSN: 1478-811X