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Fig. 2 | Cell Communication and Signaling

Fig. 2

From: Andrew H. Wyllie, a pioneer in the field of apoptosis

Fig. 2

Original scheme of apoptosis as described by Kerr, Wyllie, and Currie [1972]. As defined by Wyllie and others, typical apoptosis is now considered to include Cleavage of HMW DNA, Chromatin condensation, Chromatin margination to nuclear membrane, Nuclear membrane shrinkage, Oligonucleosomal cleavage of DNA, Fragmentation of nucleus, Cytoplasmic shrinkage, Rounding of cells, Formation of vacuoles in the cell, Exteriorization of phophatidylserine, Activation of caspase-3

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Cell Communication and Signaling

ISSN: 1478-811X