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Fig. 1 | Cell Communication and Signaling

Fig. 1

From: DNMT3A R882H mutation drives daunorubicin resistance in acute myeloid leukemia via regulating NRF2/NQO1 pathway

Fig. 1

DNMT3A R882H mutation promotes cell proliferation and decreases cell apoptosis A, B The expression of DNMT3A in KG-1a and THP1 cells transduced with EV, DNMT3A-WT, and DMT3A-R882H was detected by qPCR and western blotting. C The growth curves of KG-1a and THP1 cells, transduced with EV, DNMT3A-WT and R882H. D The rate of cell apoptosis was detected by flow cytometry in KG-1a and THP1 cells stably transduced with EV, DNMT3A-WT and R882H in two cell lines. E Apoptosis related protein levels were examined by western blotting

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Cell Communication and Signaling

ISSN: 1478-811X