Fig. 2
From: PGE2 promotes macrophage recruitment and neovascularization in murine wet-type AMD models
COX2 was highly expressed in the laser-injured RPE-choroid complex. A, B Immunofluorescence staining of the choroidal flat mounts A and sections B from mice (7 dpi) with anti-CD31, anti-COX2, and anti-COX1 mAbs; scale bar: 100 μm. C, D The COX2 and COX1 protein at 7 dpi was measured by western blotting using β-actin as an internal control. The representative blots are shown, with quantification (n = 6). E Quantitative analysis of PGE2 levels (n = 6). The level of PGE2 in the peripheral blood of mice (7 dpi) was measured by ELISA after the laser-induced CNV model. *P < 0.05; **P < 0.01