Fig. 7From: Sphingosine 1-phosphate receptor 2 mediated early stages of pancreatic and systemic inflammatory responses via NF-kappa B activation in acute pancreatitisSchematic diagram: S1PR2 mediates early activation of inflammatory pathways, particularly though NF-kappa B activation in acinar cells, recruits macrophages, promotes macrophages polarization toward the M1 phenotype, and participates in pancreatic local and systemic inflammatory responses in acute pancreatitisBack to article page