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Fig. 3 | Cell Communication and Signaling

Fig. 3

From: Sphingosine 1-phosphate receptor 2 mediated early stages of pancreatic and systemic inflammatory responses via NF-kappa B activation in acute pancreatitis

Fig. 3

S1PR2 knockdown alleviates pancreatic damage in acute pancreatitis mice. Schematic representation of the experimental schedule (A); western blot of pancreatic S1PR2 (B); serum lipase (C) and serum amylase (D) level; ELISA of serum IL6 (E) and TNF-α (F); H&E-staining pancreas sections (G); TUNEL staining (H); Western blot of pancreatic PARP, caspase3 and NF-κB p65 (I) levels in the pancreas. Data shown are means ± SEM. ***p < 0.001 compared with the control group. #p < 0.01, ##p < 0.05 compared with the model group

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