Fig. 1
From: Targeting Endocytosis and Cell Communications in the Tumor Immune Microenvironment
Cell-to-cell communication through direct and indirect contact. Crosstalk in the tumor microenvironment can be through direct contact between adhesion molecules, or indirectly through secretion signals from extracellular vesicles. Tumor surface antigen regulation and tumor-induced immune suppression involve endocytic pathway in tumor immunity. In addition, immunosuppression may arise through accumulating and secreting exosomes around tumor