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Fig. 6 | Cell Communication and Signaling

Fig. 6

From: Cell adhesion molecule BVES functions as a suppressor of tumor cells extrusion in hepatocellular carcinoma metastasis

Fig. 6

BVES co-localized with ZO-1 and GEFT. A The representative IF staining images of extruded Huh7 cells. Red, F-actin; blue, nuclei; green, ZO-1. B IF staining showing expression and co-localization of BVES and ZO-1 in HCC cell lines. Red, ZO-1; blue, nuclei; green, BVES. C IF staining showing expression and co-localization of BVES and GEFT in HCC cell lines. Red, GEFT; blue, nuclei; green, BVES. D IF staining showing expression and co-localization of BVES and ZO-1 in HCC and adjacent nontumor tissues. Red, ZO-1; blue, nuclei; green, BVES. E IF staining showing expression and co-localization of BVES and GEFT in HCC and adjacent nontumor tissues. Red, GEFT; blue, nuclei; green, BVES. F BVES protein was immunoprecipitated from Huh7 cells and subjected to western blotting assays to detect its interaction with ZO-1 and GEFT. IgG was used as a negative control

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Cell Communication and Signaling

ISSN: 1478-811X