Skip to main content
Fig. 3 | Cell Communication and Signaling

Fig. 3

From: Cell adhesion molecule BVES functions as a suppressor of tumor cells extrusion in hepatocellular carcinoma metastasis

Fig. 3

BVES expression was decreased in HCC tissues and cells extruded. A The representative IHC images of BVES in adjacent nontumor and HCC tissue (left); IHC scores of BVES staining in human samples (right). B PCR analysis showing the mRNA expression level of BVES in HCC cell lines. C Western blotting assays showing the protein expression of BVES in HCC cell lines. D IF confocal detection of cellular BVES expression in 3D cell culture model. The arrow pointed to a cell extruded. Red, F-actin; blue, nuclei; green, BVES; and the last was the corresponding images of the cell mass under microscope. E The mRNA expression of BVES in Huh7 and Huh7-extrusion cells. Bars represent mean ± S.D. of three independent experiments, *P < 0.05, **P < 0.01

Back to article page

Cell Communication and Signaling

ISSN: 1478-811X