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Table 1 Information for the EGFR-mutant LUAD patients involved in this study

From: ARID1A deficiency reverses the response to anti-PD(L)1 therapy in EGFR-mutant lung adenocarcinoma by enhancing autophagy-inhibited type I interferon production

Variables

Patient number (n)

Sex

 

 Male

26

 Female

27

EGFR mutation types

 

 Exon 19 deletion

24

 Exon 21 L858R

29

T790M status

 

 Positive

32

 Negative

21

Age

 

 ≤ 60 years

29

 > 60 years

24

ECOG

 

 0–1

44

 2

9

Treatment information

 

 First line

 

  1st generation EGFR-TKIs

43

  3rd generation EGFR-TKIs

10

 Second line

 

  3rd generation EGFR-TKIs

40

ARID1A expression

 

 High expression

31

 Low expression

22

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Cell Communication and Signaling

ISSN: 1478-811X