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Fig. 6 | Cell Communication and Signaling

Fig. 6

From: ARID1A deficiency reverses the response to anti-PD(L)1 therapy in EGFR-mutant lung adenocarcinoma by enhancing autophagy-inhibited type I interferon production

Fig. 6

EGFR-mutant lung adenocarcinoma patients with low ARID1A expression have enhanced immune cell filtration and a favorable response to anti-PD(L)1 therapy. A Representative images for IHC examination of ARID1A protein. B Survival analysis of progression-free survival of EGFR-mutant lung adenocarcinoma patients who received immune checkpoint inhibitors divided by ARID1A expression. C Representative images for the immunofluorescence assay to evaluate immune cell infiltration in EGFR-mutant lung adenocarcinoma patients. D Low ARID1A expression was associated with higher arbitrary units of CD3 and CD8, as revealed by the immunofluorescence assay. E ARID1A correlates negatively with immune cell infiltration in EGFR-mutant lung adenocarcinoma patients

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Cell Communication and Signaling

ISSN: 1478-811X