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Fig. 5 | Cell Communication and Signaling

Fig. 5

From: ARID1A deficiency reverses the response to anti-PD(L)1 therapy in EGFR-mutant lung adenocarcinoma by enhancing autophagy-inhibited type I interferon production

Fig. 5

Inhibition of autophagy in EGFR-mutant lung adenocarcinoma cells reverses production of type I interferon, with a similar effect as ARID1A knockdown. A Expression evaluation of targeted proteins revealed by western blotting (3-MA: 2 mM; rapamycin: 100 µM). B Schematic diagram elucidates the mechanism of ARID1A knockdown in enhancing production of type I interferon in EGFR-mutant lung adenocarcinoma cells

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Cell Communication and Signaling

ISSN: 1478-811X