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Fig. 3 | Cell Communication and Signaling

Fig. 3

From: ARID1A deficiency reverses the response to anti-PD(L)1 therapy in EGFR-mutant lung adenocarcinoma by enhancing autophagy-inhibited type I interferon production

Fig. 3

ARID1A-KD activates the EGFR/PI3K/Akt/mTOR signaling pathway and inhibits autophagy in EGFR-mutant lung adenocarcinoma cells. A–C Relative expression of phosphorylated proteins enriched in autophagy, the PI3K/Akt pathway and the mTOR pathway revealed by mass spectrometry. D Relative expression of autophagy-related biomarkers revealed by mass spectrometry. E Expression evaluation of targeted proteins revealed by western blotting

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Cell Communication and Signaling

ISSN: 1478-811X