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Fig. 6 | Cell Communication and Signaling

Fig. 6

From: Adagrasib, a KRAS G12C inhibitor, reverses the multidrug resistance mediated by ABCB1 in vitro and in vivo

Fig. 6

Effect of MRTX849 on the activation of AKT and ERK in cancer cells. A-D The total and phosphorylation protein level of AKT and ERK were detected by Western blot analysis. KB, KBv200, MCF-7 and MCF-7/adr cells were treated with different concentrations of MRTX849. MRTX849 at 15 μM was used as positive control for the blockade of AKT or ERK phosphorylation. GAPDH was used as the loading control

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Cell Communication and Signaling

ISSN: 1478-811X