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Fig. 2 | Cell Communication and Signaling

Fig. 2

From: Adagrasib, a KRAS G12C inhibitor, reverses the multidrug resistance mediated by ABCB1 in vitro and in vivo

Fig. 2

Potentiation of paclitaxel anticancer activity by MRTX849 in ABCB1-overexpressing MDR tumor xenograft models in vivo. A, B The change in tumor volume in tumor xenograft derived from KBv200 cells or MCF-7/adr cells. C, D Tumors were stripped and weighed at the end of the experiment. E, F Body weight of mice were measured every 3 days, and shown as the average percentage changes

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Cell Communication and Signaling

ISSN: 1478-811X