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Fig. 1 | Cell Communication and Signaling

Fig. 1

From: Adagrasib, a KRAS G12C inhibitor, reverses the multidrug resistance mediated by ABCB1 in vitro and in vivo

Fig. 1

Chemical structure of MRTX849 and cytotoxicity of MRTX849 in cancer cells. A Structure of MRTX849. B-F Cell viability curves for KB and KBv200 cells, MCF-7 and MCF-7/adr cells, S1 and S1-M1-80 cells, HEK293/Vector and HEK293/ABCB1 cells, and HEK293/Vector and HEK293/ABCG2 cells. All cell lines were incubated with MRTX849 for 72 h. All data are presented as means ± SEM

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Cell Communication and Signaling

ISSN: 1478-811X