Fig. 3From: The E3 ubiquitin ligase TRIM31 attenuates NLRP3 inflammasome activation in Helicobacter pylori-associated gastritis by regulating ROS and autophagyTRIM31 was downregulated in Hp-associated gastritis. A The differential gene analysis of RNA sequencing from gastric tissues of the chronic Hp infection group and the sham operation group. TRIM31 was significantly downregulated in Hp infection. B The mRNA expression of TRIM31 in gastric tissues of the Hp group and the sham group was measured by PCR. C The protein expression of TRIM31 in vivo was determined by western blotting. D The expression of TRIM31 in the Hp group and the sham group was assessed by the immunohistochemical method. Results are expressed as means ± SD. **P < 0.01, ***P < 0.001Back to article page