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Fig. 1 | Cell Communication and Signaling

Fig. 1

From: The E3 ubiquitin ligase TRIM31 attenuates NLRP3 inflammasome activation in Helicobacter pylori-associated gastritis by regulating ROS and autophagy

Fig. 1

NLRP3 inflammasome was activated in gastritis caused by chronic Hp infection. A The differential pathway analysis of RNA-sequencing of gastric tissues of mice with chronic Hp infection (Hp group) and mice with the sham operation (sham group). B The mRNA expression of NLRP3, ASC, and IL-1β in gastric tissues of the Hp group and the sham group was measured by PCR. C The protein expression of NLRP3, cleaved caspase-1, pro-caspase-1, cleaved IL-1β, and pro-IL-1β in vivo was determined by western blotting. Results are expressed as means ± SD. **P < 0.01, ***P < 0.001

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Cell Communication and Signaling

ISSN: 1478-811X