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Fig. 3 | Cell Communication and Signaling

Fig. 3

From: MICAL2 contributes to gastric cancer cell migration via Cdc42-dependent activation of E-cadherin/β-catenin signaling pathway

Fig. 3

The effect of MICAL2 knockdown on the expression of epithelial-to-mesenchymal (EMT)-related marker proteins. AC BGC-823 and MGC-803 cells were transfected with control siRNA or siRNA targeting MICAL2 (siMICAL2) following which the levels of E-cadherin (A), vimentin (B), and N-cadherin (C) were detected by qPCR and western blotting. D Representative immunofluorescence micrographs of BGC-823 and MGC-803 cells stained for E-cadherin. Scale bar, 10 μm. E The morphology of BGC-823 cells transfected with control siRNA or siMICAL2 was visualized using an inverted microscope. Scale bar, 20 μm. *< 0.05, **< 0.01

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