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Fig. 2 | Cell Communication and Signaling

Fig. 2

From: MICAL2 contributes to gastric cancer cell migration via Cdc42-dependent activation of E-cadherin/β-catenin signaling pathway

Fig. 2

MICAL2 regulates the migration of human gastric cancer cells. A, B BGC-823 and MGC-803 cells were transfected with control siRNA or siRNA targeting MICAL2 (siMICAL2). Total mRNA and protein extracts from these cells were analyzed for MICAL2 expression. Western blot bands corresponding to MICAL2 were quantified and normalized against GAPDH (n = 3 per group). C Representative images of transwell assays in BGC-823 and MGC-803 cells transfected with control siRNA or siMICAL2 and quantification of the cell migration rate (n = 5 per group). *P < 0.05, **P < 0.01, ***P < 0.001

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