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Fig. 1 | Cell Communication and Signaling

Fig. 1

From: MICAL2 contributes to gastric cancer cell migration via Cdc42-dependent activation of E-cadherin/β-catenin signaling pathway

Fig. 1

MICAL2 expression in gastric cancer tissues and cells. A Differences in MICAL2 expression in The Cancer Genome Atlas Stomach Adenocarcinoma (TCGA-STAD) tissues and adjacent normal tissues. B Differences in MICAL2 expression between TCGA-STAD cohort and normal samples in the Genotype-Tissue Expression (GTEx) database combined with adjacent TCGA-STAD tissue samples. C The MICAL2 mRNA level was assessed in normal gastric mucosa (n = 31), diffuse gastric adenocarcinoma (n = 6), gastric intestinal-type adenocarcinoma (n = 26), and gastric mixed adenocarcinoma (n = 4). Data from Gluck et al. D Representative images of MICAL2 staining in gastric cancer tissues and their normal controls from the Human Protein Atlas (HPA). E Kaplan–Meier analysis of overall survival (OS) for patients with low or high levels of MICAL2 expression. F MICAL2 protein levels in GES-1, SGC-7901, BGC-823, and MGC-803 cells were determined by western blotting assays. Data in (F) are presented as means ± SEM of three determinations. *P < 0.05

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Cell Communication and Signaling

ISSN: 1478-811X