Fig. 1
From: Immune system-related soluble mediators and COVID-19: basic mechanisms and clinical perspectives
The possible pathway of neutrophil extracellular trap-osis (NETosis) in airway of COVID19 infected patients. Following infection of the lung airways with the SARS-CoV-2, neutrophils recruit and activates due to the secretion of proinflammatory cytokines, DAMPs, viral components, and platelets activations, and subsequently neutrophils undergo the process of NETosis to eliminate infectious agents. This action, in turn, causes more destruction of lung airways