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Fig. 7 | Cell Communication and Signaling

Fig. 7

From: GNIP1 functions both as a scaffold protein and an E3 ubiquitin ligase to regulate autophagy in lung cancer

Fig. 7

GNIP1 increases tumour growth in vivo. A Subcutaneous tumorigenesis assay. B Detection of GNIP1 overexpression effect in A549 stable cell line. C, D Tumour weights and sizes were monitored. The p value was calculated by paired t-test (mean ± SD, n = 6). *, p < 0.05, **, p < 0.01. E, F Immunohistochemistry to detect the protein levels of Ki67, TTF1, SQSTM1 or LC3B in tumours. G Working model of GNIP1

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Cell Communication and Signaling

ISSN: 1478-811X