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Fig. 2 | Cell Communication and Signaling

Fig. 2

From: GNIP1 functions both as a scaffold protein and an E3 ubiquitin ligase to regulate autophagy in lung cancer

Fig. 2

GNIP1 promotes the proliferation and migration of NSCLC cells. A, B Cell counting experiment detected the growth of H1299 and A549 cells after overexpression of GNIP1. Data are presented as the average of three independent experiments (mean ± SD). ****, p < 0.0001. C, D The scratch wound healing assays of H1299 and A549 cells with or without exogenous GNIP1 expression (upper panel). Statistical analysis of cell scratch wound healing assays between groups (lower panel). Data are presented as the average of three independent experiments (mean ± SD). **, p < 0.01, ****, p < 0.0001 E, F Transwell assays of H1299 and A549 cells with or without ectopic GNIP1 expression. G, H F-actin staining assays of H1299 and A549 cells with or without exogenous GNIP1 expression

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Cell Communication and Signaling

ISSN: 1478-811X