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Fig. 9 | Cell Communication and Signaling

Fig. 9

From: Alpha5 nicotinic acetylcholine receptor mediated immune escape of lung adenocarcinoma via STAT3/Jab1-PD-L1 signalling

Fig. 9

α5-nAChR promotes tumour growth and immune escape by upregulating PD-L1 in C57BL/6 mice model. A Stable α5-nAChR overexpression upregulated PD-L1 expression. B The morphology of tumour xenografts from each mouse was photographed. C The expression level of PD-L1, CD4 and GB within tumour xenografts in each group of C57BL/6 mice, N = 5 mice/group. Scare bar, 100 μm. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001

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Cell Communication and Signaling

ISSN: 1478-811X