Fig. 7From: Alpha5 nicotinic acetylcholine receptor mediated immune escape of lung adenocarcinoma via STAT3/Jab1-PD-L1 signallingα5-nAChR, PD-L1, Jab1 and pSTAT3 expression in LUAD tumour xenograft tissues of nude mice. A α5-nAChR expression in NC, NC + nicotine, KD and KD + nicotine groups. B PD-L1 expression in NC, NC + nicotine, KD and KD + nicotine groups. C Jab1 expression in NC, NC + nicotine, KD and KD + nicotine groups. D pSTAT3 expression in NC, NC + nicotine, KD and KD + nicotine groups. Scare bar, 100 μm. Data are presented as the mean ± SEM of three independent experiments. *P < 0.05, **P < 0.01Back to article page