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Fig. 6 | Cell Communication and Signaling

Fig. 6

From: Alpha5 nicotinic acetylcholine receptor mediated immune escape of lung adenocarcinoma via STAT3/Jab1-PD-L1 signalling

Fig. 6

α5-nAChR mediates T cell activity in the coculture system. A CHRNA5 expression was positively correlated with Tregs. B, C Tregs in T lymphocytes cocultured with A549 and H1299 cells. D, E IFN-γ and IL-2 levels in the coculture supernatant. F T cell-mediated cell killing by CCK-8 assay. G T cell-regulated tumour cell killing by crystal violet staining. Data are presented as the mean ± SEM of three independent experiments. *P < 0.05, **P < 0.01

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Cell Communication and Signaling

ISSN: 1478-811X