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Fig. 5 | Cell Communication and Signaling

Fig. 5

From: Alpha5 nicotinic acetylcholine receptor mediated immune escape of lung adenocarcinoma via STAT3/Jab1-PD-L1 signalling

Fig. 5

Jab1 stabilizes PD-L1 expression in LUAD cells. A PD-L1 expression in the si-NC or si-COPS5 groups treated with 50 μg/ml CHX. B PD-L1 expression in the si-NC or si-COPS5 groups treated with 10 μM MG-132 for 24 h. C Immunofluorescence staining of PD-L1 (green) and Jab1 (red). Scale bar, 100 μm. D The STAT3 binding site of the human Jab1 and PD-L1 promoter. Data are presented as the mean ± SEM of three independent experiments. **P < 0.01

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Cell Communication and Signaling

ISSN: 1478-811X