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Fig. 3 | Cell Communication and Signaling

Fig. 3

From: Alpha5 nicotinic acetylcholine receptor mediated immune escape of lung adenocarcinoma via STAT3/Jab1-PD-L1 signalling

Fig. 3

α5-nAChR mediates pSTAT3, Jab1 and PD-L1 expression in vitro. A, B Silencing α5-nAChR downregulated pSTAT3, Jab1 and PD-L1 expression in A549 cells and H1299 cells. C, D Nicotine promoted α5-nAChR, pSTAT3, Jab1 and PD-L1 expression in A549 cells and H1299 cells. Data are presented as the mean ± SEM of three independent experiments. **P < 0.01, ns not significantly different

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Cell Communication and Signaling

ISSN: 1478-811X