Fig. 8
From: Lamprey immune protein triggers the ferroptosis pathway during zebrafish embryonic development
Network visualization of key signaling and lip regulatory modules implicated in ferroptosis. The gene regulatory network comprises the following circuits (in chronological order of execution): 1. Iron overload; 2. Lipid peroxidation 3. Ferroptosis and 4. Mitochondrial damage and pericardial edema. Full protein names of the nodes in this network are as follows: TF: transferrin, TFR: transferrin receptor, ACSL4: acyl-CoA synthetase long chain family member 4