Fig. 4
From: THZ1 targeting CDK7 suppresses c-KIT transcriptional activity in gastrointestinal stromal tumours
THZ1 shows antineoplastic properties in vivo. A Images of subcutaneous tumours from the vehicle or THZ1 treatment groups (n = 5). B, C. Tumour volume and weight of the subcutaneous tumour model. THZ1 treatment led to a significant reduction in tumour volume and weight. C Immunohistochemistry staining of Ki67 and cleaved caspase-3 in tissue sections from vehicle- or THZ1-treated subcutaneous tumours