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Table 2 Correlation coefficients for proteins colocalized with TRPC1 before and during SOCE

From: How filopodia respond to calcium in the absence of a calcium-binding structural protein: non-channel functions of TRP

Experimental phase

Untreated

ER depletion

Ca2+ replenishment

AQP4

   

Correlation coefficient

0.727†,‡

0.845

0.910

Standard error

0.039

0.019

0.020

 

8

6

8

STIM1

Correlation coefficient

0.465§

0.490

0.786§,

Standard error

0.033

0.029

0.026

Number of images

17

6

7

Vamp2

Correlation coefficient

0.546¶,#

0.714

0.791#

Standard error

0.033

0.054

0.040

Number of images

8

6

7

  1. Peripheral cytoplasm from images processed by Colocalization Finder (see “Immunofluorescence localization, image acquisition, and image processing” section)
  2. ANOVA on experiment, P = 0.00037, treatments differ at P = 0.0188
  3. Treatments differ at P = 0.00049
  4. §ANOVA on experiment, P < 0.00001, treatments differ at P = 0.00001
  5. Treatments differ at P = 0.00002
  6. ANOVA on experiment, P = 0.00047, treatments differ at P = 0.014
  7. #treatments differ at P = 0.00061