Fig. 1

RNAseq expression profiling for key CSC/mPR/nPR players utilizing The Cancer Genome Atlas (TCGA) breast cancer database: We investigated key CSC, mPRs and nPR players expression analysis using both types of 'normal' tissues; “tissue normal” which are taken from normal tissue, near the tumor site, and “normal tissue” from individuals without cancer. A CmPn expression profiles based on tissue type. B CmPn expression profiles between Luminal-type cancers. C CmPn expression profiles, based on HER2 status, between Luminal-type breast cancers. D CmPn expression profiles based on clinical tumor (T) staging in Luminal-A breast tumors. E CmPn expression profiles based on lymph node (N) staging in Luminal-A breast tumors. F CmPn expression profiles based on metastases (M) staging in Luminal-A breast tumors. For all graphs, X axis details genes profiled, while Y axis details Log2 RSEM normalized RNAseq expression data (panel A), Log2 batch-effect normalized RNAseq expression data (panels B–C) or Log2 PANCAN normalized (panels D–F) RNAseq expression data (mean-centered). All graphs were produced using the Xena platform. Significance was performed automatically by the Xena platform using One-way ANOVA and default parameters. For legend details for panels D–F, see end of Additional file 1: Fig S10 legend