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Fig. 3 | Cell Communication and Signaling

Fig. 3

From: STAT3-mediated osteogenesis and osteoclastogenesis in osteoporosis

Fig. 3

Jak2/STAT3 signal network negatively regulates osteogenic differentiation. JAK/STAT3 mediated signaling pathway and interlinked network that negatively regulation of osteogenesis via regulating activations of JAK and/or STAT3, a complicated and stimulator-specific role of STAT3 were indicated and marked with event-specific colored line or arrows. Ending with red bars indicate inhibition or downregulation, arrows indicate positive stimulation or upregulation

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Cell Communication and Signaling

ISSN: 1478-811X