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Fig. 3 | Cell Communication and Signaling

Fig. 3

From: Cellular crosstalk during liver regeneration: unity in diversity

Fig. 3

Cellular crosstalk in transdifferentiation of hepatic epithelial cells. Mechanisms required for reciprocal transdifferentiation of hepatocytes and cholangiocytes partially overlap; LSECs promote the transdifferentiation of LPCs by secreting cytokines; HSCs provide a specific microenvironment for the transdifferentiation of bipotential BECs by tightly cooperating with the ECM and cytokines/growth factors; KCs chemotactic by BECs can promote the transdifferentiation of liver epithelial cells by secreting cytokines

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Cell Communication and Signaling

ISSN: 1478-811X