Fig. 4From: Circular dorsal ruffles disturb the growth factor-induced PI3K-AKT pathway in hepatocellular carcinoma Hep3B cellsCorrelation between AKT phosphorylation and CDR formation in Hep3B cells after growth factor stimulation. A and D Time course of signaling in response to EGF (160Â nM) (A) and insulin (100Â nM) (D). B and E Quantification of the pAKT/AKT ratio at the indicated times after EGF (B) or insulin (E) stimulations from three independent experiments. C and F The frequency of cells showing CDRs at the indicated times after EGF (C) or insulin (F) stimulations from three independent experimentsBack to article page