Fig. 3From: Circular dorsal ruffles disturb the growth factor-induced PI3K-AKT pathway in hepatocellular carcinoma Hep3B cellsSEM images of growth factor-induced CDRs in Hep3B cells. Representative images of advanced SEM showing CDRs induced in Hep3B cells by EGF (A) and insulin (B) treatment (3 min). Lamellipodia (red arrows) are vertically evoked from the surface of cells to form CDRs, whereas the structures are disconnected at several locations (white arrows). Scale bars: 10 μmBack to article page