Fig. 1

Growth factor stimulation induces CDRs in Hep3B cells. A–G Representative confocal images of actin in MDA-MB-231 (A), MCF-7 (B), BxPC-3 (C), LO2 (D), Huh7 (E), HepG2 (F), and Hep3B (G) cell lines after EGF (160 nM) or insulin (100 nM) treatment (3 min). Cells were starved overnight and stimulated by the ligands. CDRs (arrows) were identified in Hep3B but not in other cell lines. H Representative confocal images of actin in Hep3B under culture condition. CDRs (arrows) were occasionally identified. Scale bars: 25 μm