Fig. 6

Investigation of anti-IFN-α autoantibody existence in COVID-19 patients and its correlation with IFN-α level: A Evaluation of anti-IFN-α autoantibody existence in COVID-19 patients (mild and severe condition) and healthy controls using ELISA (Median values for health controls, COVID-19 patients with mild and severe conditions are 0.375, 0.36, and 0.5150, respectively); Graphs are presented as dot plots with negative and positive controls. The calculated cut-off index was 0.748 nm and presented by a dotted line. Three groups have the same sample size (N = 50). B Correlation of IFN-α serum level and anti-IFN-α autoantibody existence in COVID-19 patients with severe and mild symptoms using Pearson r correlation assay