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Fig. 6 | Cell Communication and Signaling

Fig. 6

From: Cholecystectomy promotes colon carcinogenesis by activating the Wnt signaling pathway by increasing the deoxycholic acid level

Fig. 6

GW4064 and GSK inhibitor rescue the promoting effect and inhibiting effect of DCA and GW4064 by regulating the cytosolic β-catenin expression in CC line cells. a, b Living-cell image was used to detect the proliferate capability of CC cells treated with DCA and DCA + GW4064. c, d Living-cell image was used to detect the proliferate capability of CC cells treated with GW4064 and GW4064 + GSK inhibitor. e Western blotting was used to detect the protein level of cytosolic β-catenin in CC cells of NC, DCA, DCA + GW4064. f Western blotting was used to detect the protein level of cytosolic β-catenin in CC cells of DMSO, GW4064, and GW4064 + GSK inhibitor. *P < 0:05, **P < 0.01, ***P < 0.001

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