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Fig. 4 | Cell Communication and Signaling

Fig. 4

From: Inhibition of AMPK/PFKFB3 mediated glycolysis synergizes with penfluridol to suppress gallbladder cancer growth

Fig. 4

AMPK inhibitor CC enhanced the anticancer effects of penfluridol. A, B The glucose consumption and lactic acid production ability of SGC-996, EH-GB1, and GBC-SD cells treated with control, 10 μM CC, 5 μM PF, and CC + PF. C The colony formation of SGC-996, EH-GB1, and GBC-SD cells were treated with control, 10 μM CC, 5 μM PF, and CC + PF for 14 days. D The Annexin V/PI staining apoptosis assay of SGC-996, EH-GB1, and GBC-SD cells treated with control, 10 μM CC, 5 μM PF, and CC + PF. E The Western blot of SGC-996, EH-GB1, and GBC-SD cells treated with control, 10 μM CC, 5 μM PF, and CC + PF. ***P < 0.001, ****P < 0.0001

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Cell Communication and Signaling

ISSN: 1478-811X