Fig. 4From: Epigenetic silencing and tumor suppressor gene of HAND2 by targeting ERK signaling in colorectal cancerHAND2 could repress tumor growth in CRC tumor xenograft. The tumor in mice (a) and the size (b, c) and weight (d) of resected tumors were significantly decreased in mice with HAND2 reconstitution compared control mice (** P < 0.01). The mice were injected with DLD1 cells with HAND2 reconstitution (DLD1-HAND2) or control vector (DLD1-cont) and were sacrificed 12d, 18d and 24d after injection subcutaneouslyBack to article page