Fig. 9From: Melanoma cells with diverse invasive potential differentially induce the activation of normal human fibroblastsCrosstalk between melanoma and CAFs. Abbreviations: MMP, matrix metalloproteinase; p-p38, phosphorylated-p38; pERK, phosphorylated extracellular signal-regulated kinase; CD44, cluster of differentiation 44; RUNX2, runt-related transcription factor 2; CCL2, C-C Motif Chemokine Ligand 2; CXCL1, C-X-C Motif Chemokine Ligand 1; GM-CSF, Granulocyte–macrophage colony-stimulating factor; ICAM1, Intercellular Adhesion Molecule 1; IL6, interleukin 6; VEGFA, vascular endothelial growth factor A; PIGF, Placental growth factor; IGFBP-2, Insulin-Like Growth Factor Binding Protein 2; DPPIV, Dipeptidyl‐peptidase VI; TGFβ, transforming growth factor-beta; Cav-1, caveolin 1; CAFs, cancer-associated fibroblastsBack to article page