Skip to main content
Fig. 5 | Cell Communication and Signaling

Fig. 5

From: Chlorogenic acid exerts neuroprotective effect against hypoxia-ischemia brain injury in neonatal rats by activating Sirt1 to regulate the Nrf2-NF-κB signaling pathway

Fig. 5

Chlorogenic acid improves hypoxic-ischemic brain injury-induced brain tissue structural damage. a Representative images of HE staining in the cortex, hippocampus CA1 region, hippocampus CA3 region, and DG region 7 days after HI injury. Scale bars represent 200μm in the images of 4X; Scale bars represent 100μm in the images of 10X; Scale bars represent 50μm in the images of 20X. Scale bars represent 20μm in the images of 40X. b Representative images of Nissl staining in the cortex, hippocampus CA1 region, hippocampus CA3 region, and DG region 7 days after HI injury. Scale bars represent 200μm in the images of 4X, Scale bars represent 100μm in the images of 10X, Scale bars represent 50μm in the images of 20X. Scale bars represent 20μm in the images of 40X. c–f Cell numbers in the cortex of the images of 10X, hippocampus CA1 region, hippocampus CA3 region, and DG region in each group,results of treatments are based on the 600mg/kg of CGA. ∗∗∗P < 0.001 vs. the sham group. #P < 0.05, ##P < 0.01 and ###P < 0.001 vs. the HI group. &P < 0.05, &&P < 0.01, &&&P < 0.001 vs. the CA treatment group. n = 3

Back to article page

Cell Communication and Signaling

ISSN: 1478-811X