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Fig. 4 | Cell Communication and Signaling

Fig. 4

From: Chlorogenic acid exerts neuroprotective effect against hypoxia-ischemia brain injury in neonatal rats by activating Sirt1 to regulate the Nrf2-NF-κB signaling pathway

Fig. 4

Chlorogenic acid (CA) treatment reduces HI-induced neuronal apoptosis. a Western blot evaluation of the protein levels of Bcl2, Bax, caspase-8, caspase-8 p18, cleaved-caspase-3 and caspase-3 24h after HI injury. b Quantification of western blot data of Bcl2/Bax. c Quantification of western blot data of caspase-8 p18/caspase-8. d Quantification of western blot data of cleaved-caspase-3/caspase-3. ∗∗P < 0.01, ∗∗∗P < 0.001 vs. the sham group. #P < 0.05, ###P < 0.001 vs. the HI group. &P < 0.05, &&P < 0.01 vs. the CA treatment group. n = 3

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Cell Communication and Signaling

ISSN: 1478-811X