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Fig. 1 | Cell Communication and Signaling

Fig. 1

From: Chlorogenic acid exerts neuroprotective effect against hypoxia-ischemia brain injury in neonatal rats by activating Sirt1 to regulate the Nrf2-NF-κB signaling pathway

Fig. 1

Chlorogenic acid-induced attenuation of hypoxic-ischemic brain injury in neonatal rats. a Representative images of TTC-stained coronal brain sections 24 h after HI brain injury with/without treatments. b Calculation of the infarct area depicted by TTC staining. P < 0.001 vs. the sham group. #P < 0.05, ##P < 0.01 and ###P < 0.001 vs. the HI group. &P < 0.05, &&P < 0.01 vs. the CGA (150mg/kg) group. n = 4. c The brains isolated from each group 7days after HI brain injury. d The ratio of residual brain volume calculated in each group. P < 0.001 vs. the sham group. #P < 0.05 vs. the HI group. n = 5

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