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Fig. 8 | Cell Communication and Signaling

Fig. 8

From: tRF-Val-CAC-016 modulates the transduction of CACNA1d-mediated MAPK signaling pathways to suppress the proliferation of gastric carcinoma

Fig. 8

pcDNA-CACNA1d strengthened the proliferation of GC and was modulated by tRF-Val-CAC-016 mimics. tRF-Val-CAC-016 mimics could significantly reverse the reinforced effect of pcDNA-CACNA1d on the proliferation of GC cells in terms of the CCK-8 (a–b), EdU (c–d), flow cytometry for cell cycle (e–g) and colony formation assays (h–i). j–k pcDNA-CACNA1d significantly lifted the protein levels of CACNA1d, CyclinD1, CyclinB, c-myc, and tRF-Val-CAC-016 mimics could decline this function. *P < 0.05, **P < 0.01, statistically significant

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Cell Communication and Signaling

ISSN: 1478-811X