Fig. 1
From: Co-targeting WIP1 and PARP induces synthetic lethality in hepatocellular carcinoma
High expression of WIP1 correlates with a poor prognosis in HCC. A WIP1 mRNA expression of normal liver tissues and hepatocellular carcinoma of Roessler Liver 2 cohort in Oncomine database (t-test; p < 0.01). B Expression of WIP1 mRNA in 37 pairs of liver cancer tissues and adjacent non-tumor tissues from GEO data sets GES57957 (Paired t test; p < 0.01). C The mRNA expression levels of WIP1 in liver cancer cell lines and normal liver cell line (Chang) was detected via qRT-PCR. D Expression of WIP1 protein in 9 pairs of liver cancer tissues and adjacent non-tumor tissues was analyzed by Western blotting. E The expression of WIP1 mRNA levels in different American Joint Committee on Cancer Tumor Stage Code of TCGA. (Spearman p value < 0.05). F The impact of WIP1 mRNA expression on overall survival (OS) was analyzed by Kaplan–Meier survival curve (patients were grouped based on median WIP1 mRNA expression)