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Fig. 1 | Cell Communication and Signaling

Fig. 1

From: A functional role of S100A4/non-muscle myosin IIA axis for pro-tumorigenic vascular functions in glioblastoma

Fig. 1

Overexpression of S100A4 under hypoxic conditions in GBMs. A Upper: staining by HE and IHC for the indicated proteins in GBMs. Note the strong immunoreactivity for S100A4, NMIIA, HIF-1α, and CA9 in both non-Ps and Ps perinecrotic lesions. Necrotic areas are indicated by asterisks and partitioned by dotted lines. Insets show the magnified views of the boxed area. Original magnification, × 100 and × 400 (inset). Scale bar = 200 μm. Lower: IHC score for the indicated molecules in non-Ps and Ps perinecrotic (non-Ps and Ps) and non-necrotic lesions (non-nec). The data are presented as means ± SDs. B Correlation between IHC scores of S100A4 and related molecules in GBM. ρ, Spearman’s correlation coefficient; n, number of cases

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Cell Communication and Signaling

ISSN: 1478-811X